Conformational selection in protein binding and function
نویسندگان
چکیده
منابع مشابه
Conformational selection in protein binding and function.
Protein binding and function often involves conformational changes. Advanced nuclear magnetic resonance (NMR) experiments indicate that these conformational changes can occur in the absence of ligand molecules (or with bound ligands), and that the ligands may "select" protein conformations for binding (or unbinding). In this review, we argue that this conformational selection requires transitio...
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ژورنال
عنوان ژورنال: Protein Science
سال: 2014
ISSN: 0961-8368
DOI: 10.1002/pro.2539